Who We Are
The Oncology Research Information Exchange Network® (ORIEN) is a growing alliance of leading cancer centers committed to speeding up research through collaboration and access to shared patient data. ORIEN® member cancer centers use Total Cancer Care® (TCC) to learn from patients' health information and develop new cancer treatments.
Our Mission and Vision
We are on a mission to accelerate cancer research and deliver hope through collaborative learning and partnerships.
Our vision is to become leaders in creating and delivering health informatics solutions through evidence-based approaches that allow doctors to predict patient needs.
Oncology Research Information Exchange Network® (ORIEN) Members
ORIEN® Origins
ORIEN® started with visionaries at the Moffitt Cancer Center and an idea that we need patients as partners to tackle cancer. At the heart of it all was Dr. William S. Dalton, who connected with his network within Moffitt to launch the TCC® research study in 2006. To establish a bioinformatics and operational backbone of TCC®, Dr. Dalton also founded M2GEN (now Aster Insights).
With the shared goal of enriching and growing the database, ORIEN was founded in 2014 by Moffitt, M2GEN, and The Ohio State University Comprehensive Cancer Center.
Today, ORIEN® is an alliance of cancer centers, powered by Aster Insights, working in close collaboration to accomplish more in the fight against cancer. As the largest and longest-standing collaboration of academic cancer centers, we are devoted to advancing cancer research through patient-consented clinical and genomic data.
Aster Insights functions as the operations center for ORIEN® and the coordinating center for the ORIEN® TCC® research study.
Interested in Joining ORIEN®?
2006
M2GEN (Now Aster Insights) founded
First TCC® patient enrolled
2008
TCC® patient accruals reach 25k
2010
Dr. William Dalton publishes paper in AACR Journal, describing the concept or a “Research Information Exchange” which later becomes the basis for ORIEN®
2012
Five process patent Issued
2014
ORIEN® founded through partnership between Moffitt and Ohio State University
2015
ORIEN® expands to 11 members
2016
Signed first 2 ORIEN® Avatar contracts with pharmaceutical clients
ORIEN® Avatar launches and ORIEN® expands
2017
TCC® patient accruals exceed 185k
2018
ORIEN® expands and adds communication partnerships
2019
M2GEN donates $3M for inaugural ORIEN® NOVA grants
2022
TCC® accruals exceed 325,000
2024
19 ORIEN cancer center sites collaborating
TCC® accruals exceed 400,000